《英文msh词典》Cytochrome P-450 CYP11A1
[同义词] Cytochrome P-450 CYP11A1
[主题词] Cholesterol Side-Chain Cleavage Enzyme
[中文释义] 细胞色素P450 CYP11A1
[英文释义] A mitochondrial cytochrome P450 enzyme that catalyzes the side-chain cleavage of C27 CHOLESTEROL to C21 PREGNENOLONE in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme,encoded by CYP11A1 gene,catalyzes the breakage between C20 and C22 which is the initial and rate-limiting step in the biosynthesis of various gonadal and adrenal steroid hormones.