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单词 Cytochrome P450scc
释义

Cytochrome P450scc


《英文msh词典》Cytochrome P450scc
[入口词] Cytochrome P450scc
[主题词] Cholesterol Side-Chain Cleavage Enzyme
[英文释义] A mitochondrial cytochrome P450 enzyme that catalyzes the side-chain cleavage of C27 CHOLESTEROL to C21 PREGNENOLONE in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme,encoded by CYP11A1 gene,catalyzes the breakage between C20 and C22 which is the initial and rate-limiting step in the biosynthesis of various gonadal and adrenal steroid hormones.
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