单词 | ddNus |
释义 | ddNus《英文msh词典》ddNus [入口词] ddNus [主题词] Dideoxynucleosides [药动学] Reverse Transcriptase Inhibitors [英文释义] Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription. |
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